Glabridin (white gold) can penetrate the skin and maintain high activity, high efficient whitening and antioxidant. Effectively inhibits various enzyme in melanin production process the activity, especially the inhibition of tyrosinase activity. At the same time it also has to prevent rough skin and anti-inflammatory, antibacterial effect. Glabridin is at present a good curative effect, fully functional whitening ingredients. Glabridin is launched in 1989 as whitening cosmetics additive of Japanese MARUZEN company . After years of use, obvious effect, good safety. The main function is the top grade Cosmetic ingredients. Besides the Japanese cosmetics company, South Korea's widely used, Lanc o me, Dior, Sonia Rykiel, Chanel is also commonly used in the composition.
Purity: 40%,90%,98% by HPLC
Storage: 2℃-10℃, sealed, avoid light and heat.
1) whitening; inhibition of black pigment;
The experiment use UV to irradiate guinea pig brown back, then 0.5% glabridin sample applicator. Glabridin is discovered significantly reduced by UV induced pigmentation. After surface organization research can be found using melanocytes glabridin after reduction, and it can increase skin luster.
2) anti-inflammatory effect
Through experimental verification glabridin anti-inflammatory activity, to the guinea pigs under UV induced pigmentation, and then use the 0.5% glabridin solution applicator, found that glabridin reduce skin inflammation caused by uv.
3) antioxidant effect.
It shows the anti free radical oxidation effect is very strong in the cytochrome P450/NADPH oxidation system, could obviously inhibit the process of the new supersedes the old. The body of free radicals, in order not to be sensitive to oxidation of biological macromolecules (low density lipoprotein LDL, DNA) and cell wall by the oxidation of free radicals.
Anti free radical oxidation effect, prevention and free radical oxidation of diseases, such as atherosclerosis, cell senescence.There are certain blood lipid and blood pressure lowering effect.
Italian research also confirmed glabridin appetite suppressant, it can reduce the fat but not lose weight.
Form: glabridin 40% is shallow brown; 90% is a kind of white powder, insoluble in water, soluble in ethanol, propylene glycol, 1,3- butanediol etc..
Active ingredients: glabridin content ≥ 40 (HPLC): -90%
Loss on drying: ≤ 3%
Grain size: 100% pass 100 mesh
Heavy metal: ≤ 20 ppm
Arsenic (As): 2ppm
The total number of bacteria: ≤ 1000 cfu/g
Yeasts and molds: ≤ 100 cfu/g
Escherichia coli: not detected
Salmonella: not detected
Staphylococcus glucose cocci: not detected
In cosmetics, in order to achieve the whitening effect, glabridin 0.001-1.5% is recommended dosage , 0.001-0.5% is preferred. And 1, 3- butanediol and 1:10 or PEG-400 with a ratio of 1:8, dissolved, add to the final stage of low temperature formula. Topical glabridin can inhibit melanin formation, it has excellent tyrosinase inhibitory activity, can prevent skin tanning, sunburn spot and line, recommended dosage is 0.0007-0.05%. If in order to suppress male hormones and treatment of acne, glabridin was 0.01-0.5%.
98% white powder 90% off-white powder 40% brown powder or off-white powder
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